COVID-19 - On the Ground

[KUTradition]

you don’t just come off that way, gutter

i guarantee you’re smarter

[DeletedUser]

I could be wrong, but I think her 220 million remark (instead of 220 thousand) was from several years ago.

[RainbowsandUnicorns]

I could be wrong, but I think her 220 million remark (instead of 220 thousand) was from several years ago.

Don't think - because you're not wrong.

[Shirley]

I could be wrong, but I think her 220 million remark (instead of 220 thousand) was from several years ago.

^^^

She misspoke in Charlotte, North Carolina, on Oct. 21, 2020, and said "million" when she meant "thousand".

I say we lynch her.

[jhawks99]

I could be wrong, but I think her 220 million remark (instead of 220 thousand) was from several years ago.

^^^

She misspoke in Charlotte, North Carolina, on Oct. 21, 2020, and said "million" when she meant "thousand".

I say we lynch her.

She was probably wearing a tan pants suit when she said it.

[TDub]

No comments on Giggles’ assertion today that 220 million Americans died of COVID?!?

I had no idea that 2 out of every 3 people in the U.S. died. I don’t know how I failed to notice!

Thank goodness we have such a scary smart individual in charge to learn us what we need to know!

Wait. DO accuracy and facts matter now? I can't keep up.

Apparently not.

Do YOU not get the irony?

[Overlander]

So, Trump was correct when he said that we defended the airports from the British?

[JKLivin]

I could be wrong, but I think her 220 million remark (instead of 220 thousand) was from several years ago.

^^^

She misspoke in Charlotte, North Carolina, on Oct. 21, 2020, and said "million" when she meant "thousand".

I say we lynch her.

https://x.com/JamesSpiro/status/1828348822084268234

https://www.yahoo.com/news/fact-check-k ... 00244.html

Yeah, not just several years ago. But I get that this level of stupid is hard to keep track of.

Whatever, though.

[Shirley]

I could be wrong, but I think her 220 million remark (instead of 220 thousand) was from several years ago.

^^^

She misspoke in Charlotte, North Carolina, on Oct. 21, 2020, and said "million" when she meant "thousand".

I say we lynch her.

https://x.com/JamesSpiro/status/1828348822084268234

https://www.yahoo.com/news/fact-check-k ... 00244.html

Yeah, not just several years ago. But I get that this level of stupid is hard to keep track of.

Whatever, though.

You've got her now, go for the throat!

[Shirley]

Newly discovered antibody protects against all COVID-19 variants

Researchers have discovered an antibody able to neutralize all known variants of SARS-CoV-2, the virus that causes COVID-19, as well as distantly related SARS-like coronaviruses that infect other animals.

As part of a new study on hybrid immunity to the virus, the large, multi-institution research team led by The University of Texas at Austin discovered and isolated a broadly neutralizing plasma antibody, called SC27, from a single patient. Using technology developed over several years of research into antibody response, the team led by UT engineers and scientists obtained the exact molecular sequence of the antibody, opening the possibility of manufacturing it on a larger scale for future treatments.

"The discovery of SC27, and other antibodies like it in the future, will help us better protect the population against current and future COVID variants," said Jason Lavinder, a research assistant professor in the Cockrell School of Engineering's McKetta Department of Chemical Engineering and one of the leaders of the new research, which was recently published in Cell Reports Medicine.

During the more than four years since the discovery of COVID-19, the virus that causes it has rapidly evolved. Each new variant has displayed different characteristics, many of which made them more resistant to vaccines and other treatments.

Protective antibodies bind to a part of the virus called the spike protein that acts as an anchor point for the virus to attach to and infect the cells in the body. By blocking the spike protein, the antibodies prevent this interaction and, therefore, also prevent infection.

SC27 recognized the different characteristics of the spike proteins in the many COVID variants. Fellow UT researchers, who were the first to decode the structure of the original spike protein and paved the way for vaccines and other treatments, verified SC27's capabilities.

The technology used to isolate the antibody, termed Ig-Seq, gives researchers a closer look at the antibody response to infection and vaccination using a combination of single-cell DNA sequencing and proteomics.

"One goal of this research, and vaccinology in general, is to work toward a universal vaccine that can generate antibodies and create an immune response with broad protection to a rapidly mutating virus," said Will Voss, a recent Ph.D. graduate in cell and molecular biology in UT's College of Natural Sciences, who co-led the study.

In addition to the discovery of this antibody, the research found that hybrid immunity—a combination of both infection and vaccination—offers increased antibody-based protection against future exposure compared with infection or vaccination alone.

The work comes amid another summer COVID spike. This trend shows that while the worst of the pandemic may have passed, there's still a need for innovative solutions to help people avoid and treat the virus.

The researchers have filed a patent application for SC27.

[Overlander]

Newly discovered antibody protects against all COVID-19 variants

Researchers have discovered an antibody able to neutralize all known variants of SARS-CoV-2, the virus that causes COVID-19, as well as distantly related SARS-like coronaviruses that infect other animals.

As part of a new study on hybrid immunity to the virus, the large, multi-institution research team led by The University of Texas at Austin discovered and isolated a broadly neutralizing plasma antibody, called SC27, from a single patient. Using technology developed over several years of research into antibody response, the team led by UT engineers and scientists obtained the exact molecular sequence of the antibody, opening the possibility of manufacturing it on a larger scale for future treatments.

"The discovery of SC27, and other antibodies like it in the future, will help us better protect the population against current and future COVID variants," said Jason Lavinder, a research assistant professor in the Cockrell School of Engineering's McKetta Department of Chemical Engineering and one of the leaders of the new research, which was recently published in Cell Reports Medicine.

During the more than four years since the discovery of COVID-19, the virus that causes it has rapidly evolved. Each new variant has displayed different characteristics, many of which made them more resistant to vaccines and other treatments.

Protective antibodies bind to a part of the virus called the spike protein that acts as an anchor point for the virus to attach to and infect the cells in the body. By blocking the spike protein, the antibodies prevent this interaction and, therefore, also prevent infection.

SC27 recognized the different characteristics of the spike proteins in the many COVID variants. Fellow UT researchers, who were the first to decode the structure of the original spike protein and paved the way for vaccines and other treatments, verified SC27's capabilities.

The technology used to isolate the antibody, termed Ig-Seq, gives researchers a closer look at the antibody response to infection and vaccination using a combination of single-cell DNA sequencing and proteomics.

"One goal of this research, and vaccinology in general, is to work toward a universal vaccine that can generate antibodies and create an immune response with broad protection to a rapidly mutating virus," said Will Voss, a recent Ph.D. graduate in cell and molecular biology in UT's College of Natural Sciences, who co-led the study.

In addition to the discovery of this antibody, the research found that hybrid immunity—a combination of both infection and vaccination—offers increased antibody-based protection against future exposure compared with infection or vaccination alone.

The work comes amid another summer COVID spike. This trend shows that while the worst of the pandemic may have passed, there's still a need for innovative solutions to help people avoid and treat the virus.

The researchers have filed a patent application for SC27.

Thank my wife next time you see her.

She isn’t quite at the level of expertise that Randy is regarding virus research….but the entire UT microbiology group is doing some amazing things.

[RainbowsandUnicorns]

I broke my cherry! First time for everything.

[TDub]

I wonder how many times I've had it now...pretty sure I had it at least once last year but probably twice and maybe 3 times. but I quit testing like 3 years ago

[jhawks99]

Be well, Gutter

[Shirley]

Sorry to see that Gutter. Hopefully "it's no worse than a cold".

[RainbowsandUnicorns]

Be well, Gutter

Thanks. I don't want to jinx myself but right now it's not much more than a fever and feeling a little "off".

[RainbowsandUnicorns]

Sorry to see that Gutter. Hopefully "it's no worse than a cold".

Thanks - not even a cold. yet. More like flu. Fever and feeling a little "off".

[Overlander]

For the record, I feel fine

[RainbowsandUnicorns]

For the record, I feel fine

Good!

[RainbowsandUnicorns]

Did anyone take Paxlovid for Covid?
Had a video call with my doc yesterday. Pros and cons to my taking it. One con is I would have to go off my cholesterol med for 8 days but he claims it wouldn't be a big deal (especially being that I just had my cholesterol checked and it was outstanding). At the end of conversation it was decided if I feel worse this morning I should probably start taking it. I do feel a little worse this morning but not a lot worse. Seems like I may be damned if I do take it and/or damned if I don't. I don't know what to do.